I was on Cymbalta for over 7 months. The side effects are HORRIBLE!!! I finally managed to get off of it but it took several weeks of decreasing it gradually to accomplish that. Whatever you do DO NOT STOP TAKING THIS NASTY DRUG ALL AT ONCE!!!! My side effects are gone, but let me go further.
I recently became VERY depressed and stupidly thought to myself...well, maybe the Cymbalta did help with the depression...so I took one (after being off of it for several weeks). Within minutes my head began to swim...I felt faint...then the nausea began, and within minutes I was vomiting..VIOLENTLY! I could not control the nausea and vomiting, and at the same time felt like I was going to pass out at any moment. Vertigo...violent stomach pain and projectile vomiting. Couldnt keep down a cracker or a drink of water. This went on for hours. Couldnt lay down, barely sit up. This went on FOR HOURS! Luckily my neighbor was visiting when this began and she stayed with me the whole time. If I had been alone, I would have most likely have had to call an ambulance.
When it finally stopped I was drenched with sweat, had the shakes, Couldnt walk, barely talk, and she continued to stay with me until I finally went to sleep.
All of this from a drug that is supposed to help us....never again. Avoid this drug...it's poison.

Hi Paul,cymbalta made my legs jerk,but it did work.I have terrible pain in my feet from diabetic neuropathy. Do you think I should try it again? Also my feet are getting more numb every day.

Cymbalta made my arms and legs jerk so badly,had to quit.

Effexor,Cymbalta.Prestique, are all in the same family and they all screwed me up worse than I was before..agitation.anger turned to rage..i had a lot of thoughts of hurting others and killing myself...don't take it...

Apparently I have 'anger issues'...Lexapro gave me more energy but made me alot quicker 'to jump'...it brought out my anger more frequently although it wasn't more fierce - just more of it! I have been on Effexor XR 150MG for years but now I feel I needed a tweak so I'm trying low dose Prozac while I'm weaning off the Effexor. Nothing for pain right now but Gabapentin (Neurotin) and a steroid shot for arthritis and a low dose med called Meloxicam to start today. I doubt if this med will do anything but you never know.