Cymbalta (Duloxetine) for Chronic Pain

Overview
Cymbalta is a prescription drug approved by the Food and Drug Administration (FDA) to treat depression, anxiety, diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain. Cymbalta is also known by its drug name, Duloxetine.

Cymbalta is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Cymbalta is believed to work by changing the balance of neurotransmitters in the brain.

How do I take it?
Cymbalta is taken once or twice daily.

Cymbalta comes in delayed-release capsule form.

Side effects
The FDA-approved label for Cymbalta lists common side effects including drowsiness, fatigue, insomnia, dry mouth, constipation, and diarrhea.

Rare but serious side effects listed for Cymbalta include worsening depression and suicidal thoughts.