Norpramin (Desipramine) for Chronic Pain

Overview
Norpramin is a prescription medication approved by the Food and Drug Administration (FDA) for the treatment of depression. Norpramin may be mildly effective at managing neuropathic pain. Norpramin is also known by its drug name, Desipramine.

Norpramin is a tricyclic antidepressant. It is believed that Pamelor works by changing the balance of neurotransmitters in the brain.

How do I take it?
Norpramin is generally taken one or more times a day.

Norpramin is available in tablet form.

Side effects
The FDA-approved label for Norpramin lists common side effects including headache, drowsiness, lack of coordination, weakness, dry mouth, nausea, constipation, diarrhea, increased appetite, weight gain, sexual dysfunction, ringing in the ears, and blurred vision.

Rare but serious side effects listed for Norpramin include suicidality and the worsening of depressive symptoms.